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Publications

Exploring Indications for the Use of Direct Oral Anticoagulants and the Associated Risks of Major Bleeding Truman J. Milling, Jr., M.D. and Jennifer A. Frontera, M.D. Am J Manag Care. 2017;23:S67-S80.

Endovascular Thrombectomy for Ischemic Stroke: The Second Quantum Leap in Stroke Systems of Care? Warach S, Johnston SC. JAMA. 2016 Sep 27;316(12):1265-6. doi:10.1001/jama.2016.12266. No abstract available. PMID:27673304

Silent New Brain Lesions: Innocent Bystander or Guilty Party? Lee EJ, Kang DW, Warach S. J Stroke. 2016 Jan;18(1):38-49. doi: 10.5853/jos.2015.01410. Review. PMID: 26467195

Role of emergent chest radiography in evaluation of hyperacute stroke. Saber H, Silver B, Santillan A, Azarpazhooh MR, Misra VBehrouz R.  Neurology. 2016 Aug 23;87(8):782-5. doi: 10.1212/WNL.0000000000002964.

Cannabis Use and Outcomes in Patients With Aneurysmal Subarachnoid Hemorrhage. Behrouz R, Birnbaum L, Grandhi R, Johnson J, Misra V, Palacio S, Seifi A, Topel C, Garvin R, Caron JL. Stroke. 2016 May;47(5):1371-3. doi: 10.1161/STROKEAHA.116.013099.

Focal Neurological Deficit at Onset of Aneurysmal Subarachnoid Hemorrhage: Frequency and Causes. Behrouz R, Birnbaum LA, Jones PM, Topel CH, Misra V, Rabinstein AA. J Stroke Cerebrovasc Dis. 2016 Nov;25(11):2644-2647. doi: 10.1016/j.jstrokecerebrovasdis.2016.07.009.

Older Stroke Patients with High Stroke Scores Have Delayed Door-To-Needle Times. Birnbaum LA, Rodriguez JS, Topel CH, Behrouz R, Misra V, Palacio S, Patterson MG, Motz DS, Goros MW, Cornell JE, Caron JR. J Stroke Cerebrovasc Dis. 2016 Nov;25(11):2668-2672. doi: 10.1016/j.jstrokecerebrovasdis.2016.07.013.

Risk of intracerebral hemorrhage in HIV/AIDS: a systematic review and meta-analysis. Behrouz R, Topel CH, Seifi A, Birnbaum LA, Brey RL, Misra V, Di Napoli M. J Neurovirol. 2016 Oct;22(5):634-640.

Early Hypoalbuminemia is an Independent Predictor of Mortality in Aneurysmal Subarachnoid Hemorrhage. Behrouz R, Godoy DA, Topel CH, Birnbaum LA, Caron JL, Grandhi R, Johnson JN, Misra V, Seifi A, Urbansky K, Di Napoli M. Neurocrit Care. 2016 Oct;25(2):230-6. doi: 10.1007/s12028-016-0259-5

Prior Cannabis Use Is Associated with Outcome after Intracerebral Hemorrhage. Di Napoli M, Zha AM, Godoy DA, Masotti L, Schreuder FH, Popa-Wagner A, Behrouz R; MNEMONICH Registry. Cerebrovasc Dis. 2016;41(5-6):248-55. doi: 10.1159/000443532.

Prior Use of Intravenous rt-PA Improves Outcome in Endovascular Stent Retriever Trials for Acute Large Vessel Ischemic Stroke. Pitchaiah Mandava M.D., Ph.D., M.S.E.E., Sharyl R. Martini, M.D., Ph.D., Vishank A. Shah, M.D., Roderic H. Fabian, M.D., Thomas A. Kent, M.D., Michael E. DeBakey, VA Medical Center Stroke Program and Stroke Outcomes Laboratory, Department of Neurology Baylor College of Medicine, Houston, TX.

Re-Initiation of Dabigatran and Direct Factor Xa Antagonists After a Major Bleed. Milling TJ Jr, Spyropoulos AC. Am J Med. 2016 Aug 25. pii: S0002-9343(16)30662-3. doi: 10.1016/j.amjmed.2016.06.006. [Epub ahead of print]

Andexanet Alfa for Acute Major Bleeding Associated with Factor Xa Inhibitors. Connolly SJ, Milling TJ Jr, Eikelboom JW, Gibson CM, Curnutte JT, Gold A, Bronson MD, Lu G, Conley PB, Verhamme P, Schmidt J, Middeldorp S, Cohen AT, Beyer-Westendorf J, Albaladejo P, Lopez-Sendon J, Goodman S, Leeds J, Wiens BL, Siegal DM, Zotova E, Meeks B, Nakamya J, Lim WT, Crowther M; ANNEXA-4 Investigators. N Engl J Med. 2016 Aug 30. [Epub ahead of print]

Preclinical and Clinical Data for Factor Xa and “Universal” Reversal Agents. Milling TJ Jr, Kaatz S. Am J Med. 2016 Aug 26. pii: S0002-9343(16)30665-9. doi: 10.1016/j.amjmed.2016.06.009. [Epub ahead of print] Review.

Do Wake-Up Strokes Differ From Other Strokes Of Unknown Onset? Baseline Variables and Response to IV Alteplase From The Multicenter MR WITNESS Trial (NCT01282242) Steven Warach , Ona Wu, Shlee S. Song, Lawrence L. Latour, Andria L. Ford, Amie Hsia, Alona Muzikansky, Rebecca Betensky, Michael H. Lev, Pedro T. Cougo-Pinto, Gordon J. Harris, Arne Lauer, Albert J. Yoo, Lee H. Schwamm, MR WITNESS Investigators. Oral Presentation at the European Stroke Organization May 2016.

Stroke Imaging Research (STIR) and VISTA-Imaging Investigators. Acute Stroke Imaging Research Roadmap III Imaging Selection and Outcomes in Acute Stroke Reperfusion Clinical Trials: Consensus Recommendations and Further Research Priorities. Warach SJ, Luby M, Albers GW, Bammer R, Bivard A, Campbell BC, Derdeyn C, Heit JJ, Khatri P, Lansberg MG, Liebeskind DS, Majoie CB, Marks MP, Menon BK, Muir KW, Parsons MW, Vagal A, Yoo AJ, Alexandrov AV, Baron JC, Fiorella DJ, Furlan AJ, Puig J, Schellinger PD, Wintermark M. Stroke. 2016 May;47(5):1389-98.

Reinitiation of Dabigatran and Factor Xa antagonists after major hemorrhage. Milling TJ Jr, Spyropoulos A. Am J Med, Am J Emerg Med. In press 2016.

Preclinical and Clinical Data for factor Xa and “universal” reversal agents. Milling TJ Jr, Kaatz S. Am J Med, Am J Emerg Med. In press 2016.

Safety of a Four-factor Prothrombin Complex Concentrate Versus Plasma for Vitamin K Antagonist Reversal: An Integrated Analysis of Two Phase IIIb Clinical Trials. Milling TJ Jr, Refaai MA, Sarode R, et al. Acad Emerg Med. 2016 Mar 21. PMID: 26822172

Increased risk of volume overload with plasma compared with four-factor prothrombin complex concentrate for urgent vitamin K antagonist reversal. Refaai MA, Goldstein JN, Lee ML, Durn BL, Milling TJ Jr, Sarode R. Transfusion. 2015 Jul 1. PMID:26135740

Thromboembolic Events after Vitamin K Antagonist Reversal with Four-Factor Prothrombin Complex Concentrate: Exploratory Analyses of Two Randomized, Plasma-controlled Studies. Annals of Emergency Medicine. Milling T, Sarode R, Goldstein J et al. 2015 Jun 17. PMID:26135740

Four-factor prothrombin complex concentrate is superior to plasma for rapid vitamin K antagonist reversal in patients requiring urgent surgical interventions: a randomised controlled clinical trial. Goldstein J, Refaai M, Milling T et al Lancet. 2015 Feb 26. PMID:25728933

Silent new ischemic lesions after index stroke and the risk of future clinical recurrent stroke. Kang DW, Han MK, Kim HJ, Sohn H, Kim BJ, Kwon SU, Kim JS, Warach S. Neurology. 2016 Jan 19;86(3):277-85.

Identification of imaging selection patterns in acute ischemic stroke patients and the influence on treatment and clinical trial enrollment decision making. Luby M, Warach SJ, Albers GW, Baron JC, Cognard C, Dávalos A, Donnan GA, Fiebach JB, Fiehler J, Hacke W, Lansberg MG, Liebeskind DS, Mattle HP, Oppenheim C, Schellinger PD, Wardlaw JM, Wintermark M. Int J Stroke. 2016 Feb;11(2):180-Stroke Imaging Research (STIR) and VISTA-Imaging Investigators.

Acute Stroke Imaging Research Roadmap III Imaging Selection and Outcomes in Acute Stroke Reperfusion Clinical Trials: Consensus Recommendations and Further Research Priorities. Warach SJ, Luby M, Albers GW, Bammer R, Bivard A, Campbell BC, Derdeyn C, Heit JJ, Khatri P, Lansberg MG, Liebeskind DS, Majoie CB, Marks MP, Menon BK, Muir KW, Parsons MW, Vagal A, Yoo AJ, Alexandrov AV, Baron JC, Fiorella DJ, Furlan AJ, Puig J, Schellinger PD, Wintermark M; Stroke. 2016 May;47(5):1389-98.

Trauma-Specific Brain Abnormalities in Suspected Mild Traumatic Brain Injury Patients Identified in the First 48 Hours after Injury: A Blinded Magnetic Resonance Imaging Comparative Study Including Suspected Acute Minor Stroke Patients.Ricciardi MC, Bokkers RP, Butman JA, Hammoud DA, Pham DL, Warach S, Latour LL. J Neurotrauma. 2016 Jun 10. [Epub ahead of print]

Assessment of the Feasibility of Using Wearable Technology as an Innovative Tool for Telestroke Services: Initial Results of Google Glass Evaluation
Warach SJ, King BT, Chandler KV, Hartman AG, Milling TJ, European Stroke ORganisation Conference, April 17, 2015.

Clot strength as measured by thrombelastography correlates with platelet reactivity in stroke patients. Huang R, McDonald MM, Wetzel J, Kawano-Castillo J, Parker S, Archeval-Lao J, Cai C, Nguyen A, Grotta JC. Ann Clin Lab Sci (in press).

Efficacy and safety of desmoteplase administered 3 to 9 hours after ischemic stroke: the DIAS-3 randomized trial. Albers GW, VonKummer R, Truelsen T, Jensen JKS, Ravn GM, Gronning B, Chabriat J, Chang KC, Davalos AE, Ford GA, Grotta J, Kaste M, Schwamm L, Shuaib A. Lancet Neurol (DOI: 10.1016/S1474-4422(15)00047-2).

Establishing the first mobile stroke unit in the United States. Parker S, Bowry R, Wu T, Noser E, Jackson K, Richardson L, Persse, Grotta JC. Stroke 46:1384-91, 2015.

Implementing a mobile stroke unit program in the U.S.: Why, how and how much?Rajan S, Baraniuk MS, Parker S, Bowry R, Grotta JC. JAMA Neurol 72:229-34, 2015.

Mobile stroke unit hits the road in Houston.  Grotta JC, US Neurology 11:59-61, 2015.

Novel Humanized Recombinant T Cell Receptor Ligands Protect the Female Brain After Experimental Stroke. Pan J, Palmateer J, Schallert T, Hart M, Pandya A, Vandenbark AA, Offner H, and Hurn PD. Transl Stroke Res. 2014 Oct;5(5):577-85. PMCID: PMC4121525.

Stroke Neurologist’s perspective on the new endovascular trials. Grotta JC, Hacke W. Stroke (DOI:10.1161/STROKEAHA.115.008384)

Telemedicine-Guided Remote Enrollment of patients into an Acute Stroke Trial May 4, 2015 at the American Telemedicine Association Annual Meeting Los Angeles, CA.

The effects of telemedicine on racial and ethnic disparities in access to acute stroke care. Lyerly MJ, Wu TC, Mullen MT, Albright KC, Wolff C, Boehme AK, Branas CC, Grotta JC, Savitz SI, Carr BG.  J Telemed and Telecare 2015 (in press)

Thomas Willis award lecture: sex, stroke, and innovation. Hurn PD. 2014 Stroke. 2014 Dec;45(12):3725-9. PMCID: PMC4245388. [Epub 2014 Oct 21.]

Prehospital utility of rapid stroke evaluation using in-ambulance telemedicine: a pilot feasibility study. Wu TC, Nguyen C, Ankrom C, Yang J, Persse D, Vahidy F, Grotta JC and Savitz SI.  Stroke.  2014;45:2342-7.

tPA for stroke: important progress in achieving faster treatment.  Grotta JC.  Jama.  2014;311:1615-7.

CLOTBUST-Hands Free: pilot safety study of a novel operator-independent ultrasound device in patients with acute ischemic strokeBarreto AD, Alexandrov AV, Shen L, Sisson A, Bursaw AW, Sahota P, Peng H, Ardjomand-Hessabi M, Pandurengan R, Rahbar MH, Barlinn K, Indupuru H, Gonzales NR, Savitz SI and Grotta JC.  Stroke.  2013;44:3376-81.

Impact of Telemedicine on Access to Acute Stroke Care in the State of Texas.  Wu TC, Lyerly MJ, Albright KC, Ward E, Hassler A, Messier J, Wolff C, Brannas CC, Savitz SI and Carr BG.  Annals of clinical and translational neurology.  2014;1:27-33.

A pilot test of videoconferencing to improve access to a stroke risk-reduction programme for Veterans.  Anderson J, Godwin KM, Petersen NJ, Willson P and Kent TA.  Journal of telemedicine and telecare.  2013.

Prehospital thrombolysis for stroke: an idea whose golden hour has arrived.  Warach S.  JAMA neurology.  2015;72:9-10.

Targeting telestroke: benchmarking time performance in telestroke consultations. Yang JP, Wu TC, Tegeler C, Xian Y, Olson DM and Kolls BJ.  Journal of stroke and cerebrovascular diseases: the official journal of National Stroke Association.  2013;22:470-5.

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